1 - Tramadol is prescribed to treat moderate to moderately severe pain.
Tramadol belongs to the class of drugs known as opiate agonists. Primarily, tramadol works by changing the way the body senses pain. Some people mistakenly believe that tramadol is an NSAID (nonsteroidal anti-inflammatory drug), but it is not.2 - Tramadol is available in immediate release and extended release formulations.
Tramadol may be prescribed as an immediate release tablet (50 mg.) or as an extended release tablet (100, 200, or 300 mg.). The extended release tablets are usually reserved for patients with chronic pain who require continuous, long-term treatment. Your doctor will determine the appropriate dosage schedule for you.3 - Tramadol extended release tablets must be taken whole, not split, chewed or crushed.
It is important to take tramadol properly and to follow prescribing instructions. If taken improperly or in a way that is not recommended, serious side effects and even death can result.
4
- Tramadol can be habit-forming for some people.
Do not take more tramadol than has
been prescribed for you. Taking more tramadol or taking it more often can cause
dependency on it. You should also not stop taking tramadol without first
consulting your doctor. You may experience withdrawal symptoms if you stopped
it suddenly. You doctor will likely decrease your dose of tramadol gradually.
5
- Drug interactions are possible with tramadol.
Be aware of the following possible
drug interactions:
- Carbamazepine reduces the effect of tramadol
- Quinidine increases the concentration of tramadol by 50% to 60%
- Combining tramadol with an MAO (monoamine oxidase inhibitor) inhibitor or SSRI (selective serotonin reuptake inhibitors) can lead to seizures or other serious side effects.
Be sure to tell your doctor about
all medications you are taking.
6
- Tramadol, when combined with certain other substances, can increase central
nervous system and respiratory depression.
In other words, breathing may be
affected or even stop if tramadol is combined with alcohol, narcotic drugs,
anesthetics, tranquilizers, or sedatives.
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- The use of tramadol during pregnancy should be avoided.
Because the safety of tramadol use
during pregnancy has not been established, the medication should not be used
during pregnancy. The safe use of tramadol in nursing mothers has also not been
established.
8
- Tramadol is usually well-tolerated. Any side effects are usually temporary.
Some of the common side effects
associated with tramadol include:
- nausea
- constipation
- dizziness
- headache
- drowsiness
- vomiting
Less common side effects include:
itching, sweating, diarrhea, rash, dry mouth, and vertigo. There have been
patients who developed seizures after taking tramadol.
9
- A Cochrane Review of tramadol to treat osteoarthritis revealed some small
benefit.
The Cochrane Review stated that when
tramadol is taken for up to 3 months, there may be decreased pain, improvements
in function and stiffness and overall well-being. However, tramadol can cause
side effects that are significant enough to require that the patient must stop
taking the medication. Risks outweigh benefits for many people who have tried
tramadol.
10
- If an overdose of tramadol has occurred, call your local poison control
center, or call 911 if it appears to be an emergency situation.
Symptoms of an overdose include
decreased pupil size, difficulty breathing or staying awake, unconscious, coma,
heart attack, or seizure. Call for help, even if you are unsure about what to
do.
Tramadol (Ultram) is narcotic-like pain reliever used to treat moderate to severe pain. Includes tramadol side effects, interactions and indications. DB Mall
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